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ESPN FC  By ESPN staff

What's trending: Neville sacked, Messi hits 50 for Argentina, U.S. hit back

ESPN FC's Bob Ley and Kasey Keller share their takeaways from the USMNT's 4-0 thrashing of Guatemala in Columbus, Ohio.

Here are the latest stories from Wednesday.

VALENCIA: The Spanish club have sacked Gary Neville as manager. The Englishman took over in December but won just three out of 16 league games. In all competitions, Neville's record was 10 wins, seven draws and 11 defeats.

ARGENTINA: Lionel Messi has become just the second Argentina player in history to score 50 international goals after netting against Bolivia on Wednesday. Messi, 28, struck in the 30th minute of the 2018 World Cup qualifier at the Estadio Mario Alberto Kempes to reach the half-century for the Albiceleste -- a feat only ever achieved before by Gabriel Batistuta. He now stands on 499 career goals. Next up? Real Madrid.

- Argentina will return to the top of the FIFA World Ranking when the new standings are released in April, while Chile move up to a highest-ever position of third.

- Argentine forward Carlos Tevez revealed that he was never offered a Manchester United contract before his high-profile move to cross-town rivals, Manchester City.

BRAZIL: Brazil coach Dunga admits his side's qualification for the 2018 World Cup in Russia is going to be "complicated.'' The five-time world champions needed two goals in the final 10 minutes to earn a 2-2 draw with Paraguay

- Read the rest of the CONMEBOL wrap as Brazil struggled to a 2-2 draw and Colombia beat Ecuador.

UNITED STATES: Facing a must-win situation in the quest to qualify for the 2018 World Cup, the United States responded with a 4-0 victory over Guatemala on Tuesday night in Columbus, Ohio.

- Yet a banner calling for the United States to fire coach Jurgen Klinsmann flew over the Americans' World Cup qualifier.

- The United States U23s failed to qualify for consecutive Olympic men's soccer tournaments for the first time in a half century.

MEXICOMexico defeated Canada 2-0 in the Estadio Azteca to make it four wins from four on the road to Russia 2018.

- The Mexican Soccer Federation launched a campaign on Tuesday urging fans to refrain from anti-gay chants that drew fines from FIFA earlier this year.

NIGERIA: Nigeria will not be competing at the 2017 African Nations Cup after losing 1-0 to Egypt on Tuesday. Ramadan Sobhy took advantage of a missed clearance to put Egypt atop qualifying Group G at Borg El-Arab Stadium. Nigeria faced a must-win game after Chad withdrew from their group earlier this week.

MAN CITY: Manchester City defender Martin Demichelis has been charged for misconduct in relation to betting, the Football Association (FA) has announced.

ENGLAND: Roy Hodgson's frustration was clear after England's incredible win at world champions Germany was followed by an underwhelming 2-1 home defeat to Netherlands.

- Wayne Rooney has insisted that he does not take his England place for granted but believes the squad will need experienced heads at Euro 2016.

- England under-19s qualified for this summer's U19 European Championship after a 2-0 win over hosts and reigning champions Spain in the elite round qualifier.

- England goalkeeper Jack Butland has undergone a successful operation on the fractured ankle he suffered against Germany on Saturday night.

PORTUGAL: Cristiano Ronaldo scored as Portugal held on to defeat Belgium 2-1 in a game that was moved from Brussels after this month's attacks.

- However the Real Madrid man is reported to be flying to Turkey to do an advert. So close to the Clasico?

FRANCE: West Ham sensation Dimitri Payet is unsure whether his efforts for club and country have impressed national team manager Didier Deschamps enough to be included in France's Euro 2016 squad.

GERMANY: Germany coach Joachim Low claimed his team had answered their critics with a 4-1 win over Italy on Tuesday night. After throwing away a 2-0 lead to lose 3-2 against England on Saturday, the world champions beat Italy for the first time in 21 years, running out convincing winners in Munich.

LIVERPOOL: Jurgen Klopp has refused to comment on reports linking Bayern Munich attacker Mario Gotze with a switch to Liverpool this summer but did praise his former player's "extraordinary abilities."

Liverpool striker Jerome Sinclair has agreed a deal to join Watford this summer, a source close to the player has told ESPN FC.

ARSENAL: Arda Turan has said he would have settled for signing for Arsenal if his performances had not been good enough for a move to Barcelona.

- Arsene Wenger insists he has "no doubt" he'll still be at Arsenal next season and remains fully committed to the job despite the recent outpouring of criticism from fans.

REAL MADRID: Former Real Madrid player Kaka has urged supporters at the Estadio Santiago Bernabeu to stop whistling Cristiano Ronaldo.

BARCELONA: Barcelona have announced plans for a number of tributes to the late Johan Cruyff ahead of Saturday's Clasico against Real Madrid. Netherlands, Ajax and Barcelona legend Cruyff died last week at the age of 68 after suffering from lung cancer.

MAN CITY: Yaya Toure's agent says he has begun talks with European clubs as the Manchester City midfielder looks set to leave the Etihad in the summer.

CHELSEA: Eva Carneiro will begin her first new job since leaving Chelsea at a specialist medical clinic in Gibraltar on Thursday. The 42-year-old has been out of work since leaving her role as first-team doctor at Stamford Bridge under a cloud last year

ASTON VILLA: Aston Villa have announced that manager Remi Garde has left the club "by mutual consent." Villa are bottom of the Premier League, 12 points from safety with relegation to the Championship appearing a certainty.

NEWCASTLE: Martin O'Neill has revealed Rob Elliot suffered a "serious knee injury" which could end both his Euro 2016 dream and his hopes of helping to keep Newcastle in the Premier League.

SWANSEA: Swansea defender Neil Taylor has said "fantastic'' manager Brendan Rodgers would be welcomed back at Swansea. Rodgers left Swansea for Liverpool in 2012 after taking the Welsh club into the English Premier League for the first time and establishing them in the top flight.

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