Saturday, November 20, 2021
Aston Villa v Brighton
Burnley v Crystal Palace
Leicester City v Chelsea
Liverpool v Arsenal
Manchester City v Everton
Newcastle United v Brentford
Norwich City v Southampton
Tottenham Hotspur v Leeds United
Watford v Manchester United
Wolverhampton v West Ham United
Saturday, November 27, 2021
Arsenal v Newcastle United
Brentford v Everton
Brighton v Leeds United
Burnley v Tottenham Hotspur*
Chelsea v Manchester United
Crystal Palace v Aston Villa
Leicester City v Watford**
Liverpool v Southampton
Manchester City v West Ham United**
Norwich City v Wolverhampton
*Game will be moved if Spurs qualify for Europa Conference League
**Game will be moved due to Europa League involvement
Tuesday, November 30, 2021
Aston Villa v Manchester City
Everton v Liverpool
Leeds United v Crystal Palace
Manchester United v Arsenal
Watford v Chelsea
West Ham United v Brighton
Wolverhampton v Burnley
Wednesday, December 1, 2021
Newcastle United v Norwich City
Southampton v Leicester City
Tottenham Hotspur v Brentford
Saturday, December 4, 2021
Aston Villa v Leicester City
Everton v Arsenal
Leeds United v Brentford
Manchester United v Crystal Palace
Newcastle United v Burnley
Southampton v Brighton
Tottenham Hotspur v Norwich City
Watford v Manchester City
West Ham United v Chelsea
Wolverhampton v Liverpool
Saturday, December 11, 2021
Arsenal v Southampton
Brentford v Watford
Brighton v Tottenham Hotspur*
Burnley v West Ham United
Chelsea v Leeds United
Crystal Palace v Everton
Leicester City v Newcastle United
Liverpool v Aston Villa
Manchester City v Wolverhampton
Norwich City v Manchester United
*Game will be moved if Spurs qualify for Europa Conference League
Tuesday, December 14, 2021
Arsenal v West Ham United
Brentford v Manchester United
Brighton v Wolverhampton
Burnley v Watford
Crystal Palace v Southampton
Leicester City v Tottenham Hotspur
Norwich City v Aston Villa
Wednesday, December 15, 2021
Chelsea v Everton
Liverpool v Newcastle United
Manchester City v Leeds United
Saturday, December 18, 2021
Aston Villa v Burnley
Everton v Leicester City
Leeds United v Arsenal
Manchester United v Brighton
Newcastle United v Manchester City
Southampton v Brentford
Tottenham Hotspur v Liverpool
Watford v Crystal Palace
West Ham United v Norwich City
Wolverhampton v Chelsea
Sunday, December 26, 2021
Aston Villa v Chelsea
Brighton v Brentford
Burnley v Everton
Liverpool v Leeds United
Manchester City v Leicester City
Newcastle United v Manchester United
Norwich City v Arsenal
Tottenham Hotspur v Crystal Palace
West Ham United v Southampton
Wolverhampton v Watford
Tuesday, December 28, 2021
Arsenal v Wolverhampton
Brentford v Manchester City
Chelsea v Brighton
Crystal Palace v Norwich City
Everton v Newcastle United
Leeds United v Aston Villa
Leicester City v Liverpool
Manchester United v Burnley
Southampton v Tottenham Hotspur
Watford v West Ham United
Saturday, January 1, 2022
Arsenal v Manchester City
Brentford v Aston Villa
Chelsea v Liverpool
Crystal Palace v West Ham United
Everton v Brighton
Leeds United v Burnley
Leicester City v Norwich City
Manchester United v Wolverhampton
Southampton v Newcastle United
Watford v Tottenham Hotspur
Saturday, January 8, 2022
FA Cup third round
Saturday, January 15, 2022
Aston Villa v Manchester United
Brighton v Crystal Palace
Burnley v Leicester City
Liverpool v Brentford
Manchester City v Chelsea
Newcastle United v Watford
Norwich City v Everton
Tottenham Hotspur v Arsenal
West Ham United v Leeds United
Wolverhampton v Southampton
Saturday, January 22, 2022
Arsenal v Burnley
Brentford v Wolverhampton
Chelsea v Tottenham Hotspur
Crystal Palace v Liverpool
Everton v Aston Villa
Leeds United v Newcastle United
Leicester City v Brighton
Manchester United v West Ham United
Southampton v Manchester City
Watford v Norwich City
Saturday, January 29, 2022
International break weekend: World Cup qualifiers and Africa Cup of Nations (no UEFA fixtures)
Tuesday, February 8, 2022
Aston Villa v Leeds United
Brighton v Chelsea
Burnley v Manchester United
Norwich City v Crystal Palace
West Ham United v Watford
Wolverhampton v Arsenal
Wednesday, February 9, 2022
Liverpool v Leicester City
Manchester City v Brentford
Newcastle United v Everton
Tottenham Hotspur v Southampton
Saturday, February 12, 2022
Brentford v Crystal Palace
Burnley v Liverpool
Chelsea v Arsenal
Everton v Leeds United
Leicester City v West Ham United
Manchester United v Southampton
Newcastle United v Aston Villa
Norwich City v Manchester City
Tottenham Hotspur v Wolverhampton
Watford v Brighton
Saturday, February 19, 2022
Arsenal v Brentford
Aston Villa v Watford
Brighton v Burnley
Crystal Palace v Chelsea
Leeds United v Manchester United
Liverpool v Norwich City
Manchester City v Tottenham Hotspur
Southampton v Everton
West Ham United v Newcastle United
Wolverhampton v Leicester City
Saturday, February 26, 2022
Arsenal v Liverpool
Brentford v Newcastle United
Brighton v Aston Villa
Chelsea v Leicester City
Crystal Palace v Burnley
Everton v Manchester City
Leeds United v Tottenham Hotspur
Manchester United v Watford
Southampton v Norwich City
West Ham United v Wolverhampton
Sunday, February 27, 2022
Carabao Cup final
Saturday, March 5, 2022
Aston Villa v Southampton
Burnley v Chelsea
Leicester City v Leeds United
Liverpool v West Ham United
Manchester City v Manchester United
Newcastle United v Brighton
Norwich City v Brentford
Tottenham Hotspur v Everton
Watford v Arsenal
Wolverhampton v Crystal Palace
Saturday, March 12, 2022
Arsenal v Leicester City
Brentford v Burnley
Brighton v Liverpool
Chelsea v Newcastle United
Crystal Palace v Manchester City
Everton v Wolverhampton
Leeds United v Norwich City
Manchester United v Tottenham Hotspur
Southampton v Watford
West Ham United v Aston Villa
Saturday, March 19, 2022
Aston Villa v Arsenal
Burnley v Southampton
Leicester City v Brentford
Liverpool v Manchester United
Manchester City v Brighton
Newcastle United v Crystal Palace
Norwich City v Chelsea
Tottenham Hotspur v West Ham United
Watford v Everton
Wolverhampton v Leeds United
Saturday, March 26, 2022
International break weekend: World Cup qualifiers and friendlies
Saturday, April 2, 2022
Brighton v Norwich City
Burnley v Manchester City
Chelsea v Brentford
Crystal Palace v Arsenal
Leeds United v Southampton
Liverpool v Watford
Manchester United v Leicester City
Tottenham Hotspur v Newcastle United
West Ham United v Everton
Wolverhampton v Aston Villa
Saturday, April 9, 2022
Arsenal v Brighton
Aston Villa v Tottenham Hotspur
Brentford v West Ham United
Everton v Manchester United
Leicester City v Crystal Palace
Manchester City v Liverpool
Newcastle United v Wolverhampton
Norwich City v Burnley
Southampton v Chelsea
Watford v Leeds United
Saturday, April 16, 2022
Aston Villa v Liverpool
Everton v Crystal Palace
Leeds United v Chelsea
Manchester United v Norwich City
Newcastle United v Leicester City
Southampton v Arsenal
Tottenham Hotspur v Brighton
Watford v Brentford
West Ham United v Burnley
Wolverhampton v Manchester City
Saturday, April 23, 2022
Arsenal v Manchester United
Brentford v Tottenham Hotspur
Brighton v Southampton
Burnley v Wolverhampton
Chelsea v West Ham United
Crystal Palace v Leeds United
Leicester City v Aston Villa
Liverpool v Everton
Manchester City v Watford
Norwich City v Newcastle United
Saturday, April 30, 2022
Aston Villa v Norwich City
Everton v Chelsea
Leeds United v Manchester City
Manchester United v Brentford
Newcastle United v Liverpool
Southampton v Crystal Palace
Tottenham Hotspur v Leicester City
Watford v Burnley
West Ham United v Arsenal
Wolverhampton v Brighton
Saturday, May 7, 2022
Arsenal v Leeds United
Brentford v Southampton
Brighton v Manchester United
Burnley v Aston Villa
Chelsea v Wolverhampton
Crystal Palace v Watford
Leicester City v Everton
Liverpool v Tottenham Hotspur
Manchester City v Newcastle United
Norwich City v West Ham United
Saturday, May 14, 2022
FA Cup final
Sunday, May 15, 2022
Aston Villa v Crystal Palace
Everton v Brentford
Leeds United v Brighton
Manchester United v Chelsea
Newcastle United v Arsenal
Southampton v Liverpool
Tottenham Hotspur v Burnley
Watford v Leicester City
West Ham United v Manchester City
Wolverhampton v Norwich City
Sunday, May 22, 2022
Arsenal v Everton
Brentford v Leeds United
Brighton v West Ham United
Burnley v Newcastle United
Chelsea v Watford
Crystal Palace v Manchester United
Leicester City v Southampton
Liverpool v Wolverhampton
Manchester City v Aston Villa
Norwich City v Tottenham Hotspur