West Ham winger Michail Antonio looks set to be withdrawn from the England squad.
The 26-year-old played the full 90 minutes of the Hammers' 3-2 defeat by Leicester, but manager Slaven Bilic revealed afterwards he had suffered a hamstring injury.
Bilic said: "He's probably going to be withdrawn from the England squad with a hamstring problem. He felt something. He played the whole game but the medical team have told me now. He didn't limp off, though, so we will see tomorrow.''
The news will come as a blow to Antonio, who was hoping to make his international debut in the matches against Lithuania and Germany.
It also further weakens the attacking options of Three Lions boss Gareth Southgate, who is already without Harry Kane, Daniel Sturridge, Danny Welbeck and Wayne Rooney.
Southgate, who left Theo Walcott out of his squad, may now have to consider bringing in reinforcements.
The problems are piling up for West Ham manager Slaven Bilic, whose side have lost their last three matches and could yet find themselves in the relegation scrap.
"I'm very disappointed and very frustrated," he said. "We knew they had momentum, we knew they are a good side who have underachieved this season, but they scored three goals in the first half and it wasn't from chances they created.
"The first was very sloppy from us and then two set-pieces which we know they are good at - we can't concede goals like that. Then the last half an hour was probably our best of the season, but the ball just didn't want to go in. I think we deserved at least a point."