Bordeaux rallied to defeat fellow Ligue 1 side Lorient 2-1 on Tuesday to advance to the Coupe de France quarterfinals.
PSG have been on a roll of late and the return of playmaker Javier Pastore is a key addition to a side that has Ligue 1 & Champions League ambitions.
PSG coach Unai Emery has revealed the defending champions will be missing at least five regular first-team players at Niort.
Lyon goalkeeper Anthony Lopes has been suspended for one game for sparking a bizarre dispute with rivals St Etienne.
Ligue 1 leaders Monaco will face a trip to Marseille in the Coupe de France round of 16.
Unai Emery revealed his delight at his team's performance in the 4-0 thrashing of Stade Rennais in the Coupe de France round of 32 on Wednesday.