Roberto Di Matteo lost his first game since taking charge of Schalke as Bayer Leverkusen took the honours with a 1-0 win at the BayArena.
Hakan Calhanoglu netted the only goal of the game with a trademark free-kick which beat Ralf Fahrmann to lift the Werkself up to fourth in the Bundesliga.
After beating Hertha Berlin and Sporting Lisbon in his first two games in charge, Di Matteo failed to make it three out of three with defeat on his first trip away from the Arena AufSchalke to leave Schalke in...
Bayer Leverkusen boosted their hopes of advancing from Champions League Group C on Wednesday night with a 2-0 victory over previously unbeaten Zenit St Petersburg.
Second-half goals from Giulio Donati and Kyriakos Papadopoulos secured the points for Roger Schmidt's side and helped them move top of the pool, with Monaco and Benfica battling out a goalless draw.
Wendell was sent off for a second bookable offence 11 minutes from time, but the visitors could not capitalise on the extra man.