Accrington can welcome back loanees John O'Sullivan and Sean Maguire against Cambridge.
Blackburn midfielder O'Sullivan and West Ham forward Maguire were ineligible for the FA Cup first-round replay win over Notts County in midweek.
Stanley could hand a debut to new signing Matt Crooks, who signed on loan from Huddersfield on Thursday.
Midfielder Anthony Barry (knee) is back in training, while defender Adam Buxton (thigh) is making progress.
Midfielder Matty Blair could make his debut for Cambridge after...