MLS teams learned their opponents for their initial round of the U.S. Open Cup after teams in lower divisions completed the third round on Wednesday.
The fourth round sets up multiple local rivalries, with New York City FC facing the NASL's New York Cosmos and the USL's Sacramento Republic playing at the San Jose Earthquakes.
The Seattle Sounders and Portland Timbers will meet in the only all-MLS matchup.
The full schedule (all times ET):
New York City FC (MLS) at New York Cosmos (NASL),...