Alexis Sanchez key for Arsenal, Roberto Firmino to fire for Liverpool?
There's no doubting the biggest match-up of ESPN FC Premier Fantasy Gameweek 25, with the top two going toe-to-toe at The Etihad. But only a week later the stakes will go that little bit higher as Arsenal host Leicester and City go up against Spurs.
Here's how the first instalment of a potentially thrilling two gameweeks could pan out.
Arsenal, without a league win since early January, can be thankful that they're travelling to a Bournemouth side that has one of the worst home defensive records.
The Gunners pounded Southampton to no avail as they drew 0-0 in midweek, with Mesut Ozil (£9.6m) creating 10 chances -- two more than the Saints managed as a team -- and Olivier Giroud (£8.5m) racking up eight attempts and 15 penalty area touches.
Arsenal haven't scored in three league matches, but they've kept four clean sheets in the last six gameweeks, so Hector Bellerin (£6.9m) and Petr Cech (£7.0m) could prosper.
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West Brom's record on the road is sound -- only five teams have conceded fewer times than the Baggies -- but Newcastle's home form is the only thing giving them a glimmer of hope at the moment.
The Magpies have scored 19 of their 25 goals for the season at St James' Park and they'll be looking to new boy Andros Townsend (£5.4m) and possibly striker Seydou Doumbia (£6.0m) to continue that strong home showing.
Tottenham's run of six wins from their last eight league fixtures has taken them to third in the table, and the visit of a Watford side that haven't won away since Dec. 12 looks like a solid platform for more of the same from Spurs.
Dele Alli (£6.2m) and Christian Eriksen (£7.5m) are the dynamic duo in midfield. Alli has a goal and an assist from each of his last two starts but goes into the encounter as a slight injury doubt after suffering dizziness during last gameweek's clash with Norwich. Eriksen, meanwhile, has accrued an impressive three assists in his last two starts.
Spurs kept their first clean sheet since Boxing Day in the midweek win at Norwich and Toby Alderweireld (£7.0m) remains the top-rated defender in ESPN FC Premier Fantasy. For those on a budget, his new centre back partner Kevin Wimmer (£4.8m) offers great value.
Man City vs. Leicester is a tough one to predict. The league's top two scorers have also been remarkably frugal of late, with the Sky Blues keeping three clean sheets in four and the Foxes five from their last six matches.
A 0-0 seems highly unlikely however, so investing in the tried and tested talents of Sergio Aguero (£9.8m) and Jamie Vardy (£9.1m) looks wise, with David Silva (£8.0m) and Riyad Mahrez (£9.1m) also worth a look.
Alexis Sanchez (£9.1m), much like his team, did everything but score against Southampton. The Chilean had nine penalty area touches, five attempts and fired in a chance every 19.4 minutes. He also created five chances for teammates and threw in three crosses for good measure. Bournemouth beware.
Georginio Wijnaldum (£8.0m) is the major reason for Newcastle's home comforts. All nine of his goals have come at St James' Park, as have two of his four assists. The Dutchman's stats across all key areas, bar crosses and dribbling, are hugely improved at home and the visit of West Brom, without an away win since October, offers the prospect of more of the same.
Liverpool remain consistently inconsistent. In the past four gameweeks, they've drawn a blank twice and still scored eight times. Roberto Firmino (£7.0m) has hit half of those goals and has an assist as well. He looks good for more against a Sunderland side who have shipped a league-worst 34 times away from home.
Watford's frailties on the road should mean another strong showing from Harry Kane (£8.7m). Four goals and an assist in his last three outings, and an all-action midweek display involving nine penalty area touches and six attempts, points to a man in fine form.
A PUNT OR THREE
Alberto Paloschi (£5.5m) was the only late-January signing to have any real impact on his debut.
The new Swansea striker recorded a chance every 16 minutes from his second-half introduction at West Brom and he will hope to make his mark in a home match against a struggling Crystal Palace side that have lost four on the bounce and haven't won since before Christmas.
Aston Villa are staring down the barrel. The visit of Norwich represents an archetypal must-win match for both sides, but with the home side's main goal threat, Jordan Ayew (£6.0m), suspended, it is the Canaries who look the likeliest victors.
Steven Naismith (£5.8m), with a goal and an assist, and Dieumerci Mbokani (£6.1m), who also scored, caught the eye in the nine-goal thriller with Liverpool. Both offer good value against a Villa outfit that's kept only one clean sheet at home since early November.