Leicester City were unable to seal the 2015-16 Premier League title on Sunday after they drew 1-1 with Manchester United, although they could be crowned champions on Monday.
Table-toppers Leicester had to beat United at Old Trafford to secure glory but were denied by Louis van Gaal's men, to postpone their capping of a remarkable campaign.
However, should second-placed Tottenham Hotspur fail to win against Chelsea at Stamford Bridge on Monday night, Claudio Ranieri's Foxes will clinch the title.
Anthony Martial opened the scoring for United but Wes Morgan hit back for the Foxes, before Danny Drinkwater was sent off late on as Ranieri and his team were forced to wait for their historic success.
Liverpool's five-match unbeaten run in the Premier League came to an end as they were beaten 3-1 by Swansea City at the Liberty Stadium on Sunday, as the Welsh club assured of their top-flight safety.
Jurgen Klopp made eight changes to the side which lost 1-0 to Villarreal in the first leg of their Europa League semifinal on Thursday, with Daniel Sturridge returning to the starting XI.
Swansea went in front in the 20th minute when Andre Ayew headed home from close range following a dangerous corner by Gylfi Sigurdsson.
Jack Cork doubled his side's lead before the break, the midfielder curling home a superb strike beyond goalkeeper Danny Ward.
Chrstian Benteke pulled a goal back for Liverpool in the second half when he headed in from Sheyi Ojo's corner.
But Swansea restored their two-goal advantage two minutes later as Ayew netted his second of the game with a scrappy finish, before the Reds' misery was compounded with the dismissal of Brad Smith.
Sadio Mane's hat trick helped Southampton thump Manchester City's disjointed and disinterested second string 4-2 in their clash at St Mary's.
Shane Long also found the net as Saints kept their Europa League qualification bid alive, strolling home against a City lineup distracted as much by fears for their individual futures as thoughts of the Champions League.
Kelechi Iheanacho struck twice for the visitors, but Manuel Pellegrini's largely reserve line-up wilted with precious little resistance on the south coast.
City boss Pellegrini made eight changes from Tuesday's goalless Champions League semifinal first leg draw with Real Madrid, gearing up for Wednesday's return at the Bernabeu.
The Chilean duly exposed the shortcomings in his squad building at the Etihad outfit however, with many on show rightly fretting that Pep Guardiola will wield the axe on arrival at the club this summer.
Pellegrini's rotation backfired spectacularly with City yet to close out a top-four finish to guarantee Champions League football next term.
But the former Real Madrid boss can justifiably lambaste the limp performances of a host of experienced hands, who could easily be shipped out by Guardiola before next season.