Nemanja Vidic will serve a three-match suspension after Manchester United failed in an attempt to get his red card at Chelsea overturned.
Vidic, 32, will miss the second leg of the Capital One Cup semifinal against Sunderland and Premier League matches against Cardiff and Stoke after the FA confirmed his appeal was rejected by an independent regulatory commission.
The former Serbia captain was sent off in injury time of United's 3-1 defeat at Stamford Bridge for a challenge on Chelsea winger Eden Hazard.
After the match, United manager David Moyes disputed referee Phil Dowd’s decision to dismiss the Serbian, saying: “I thought Vidic wasn't a sending-off.”
However, the commission disagreed and with Vidic absent, Moyes now only has four central defenders to choose from over the next three games -- Rio Ferdinand, Jonny Evans, Chris Smalling and Phil Jones, the latter of whom played in midfield against Chelsea.
Moyes is also waiting to see if Wayne Rooney and Patrice Evra will be fit to face Sunderland.