Neymar has been ruled out of action for two weeks and will miss both the European and Spanish Super Cups after being diagnosed with parotisis (mumps).
Neymar, 23, has contracted the disease despite having already been vaccinated for mumps, and will sit out of Barca's European Super Cup against Sevilla in Tbilisi, Georgia on Tuesday.
The Brazil captain will also both legs of the Spanish Super Cup against Athletic Bilbao, due to be played on Aug. 14 and 17.
Neymar out for two weeks with parotitis (mumps) http://t.co/9vNsUFc769 #FCBlive pic.twitter.com/sY7H0SEBZ3
- FC Barcelona (@FCBarcelona) August 9, 2015
A club statement released on Sunday read: "The first team medical staff at FC Barcelona has announced on Sunday that Neymar will be out for two weeks after being diagnosed with parotitis (mumps), despite the fact that he had previously been vaccinated against the disease.
"Therefore, the Brazilian striker will miss the European Super Cup final on Tuesday in Tbilisi, Georgia against Sevilla and also the Spanish Super Cup final which sees Luis Enrique's team take on Athletic Club over two legs on 14 and 17 August."
Neymar's absence could see Manchester United target Pedro starting for Luis Enrique's side, who are looking to follow on from last season's Treble success.
The Barca squad trained for the final time in Spain before departing for Tuesday's match in Georgia, with Luis Enrique taking his full 25-man squad with the exception of Neymar.