Ajax will share their experience in nurturing young talent with Guangzhou R&F and help the Chinese club develop its own youth academy.
Four-time European champions Ajax signed a five-year, €10 million ($12m) deal on Monday, saying it will also help the Dutch club to grow.
Ajax director and former Netherlands international goalkeeper Edwin van der Sar says the youth academy "has been extremely important to Ajax for decades in everything we do."
He says sharing the knowledge with Guangzhou "is good for both clubs."
Guangzhou R&F vice president Nicky Wong says Ajax "has the best youth academy in the world" and fits the Chinese club's style of play and plans for developing talent.
He says "we have great confidence in a fruitful cooperation."